<<Emerging additive manufacturing techniques enable investigation of the effects of pore geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to test how varying pore geometry, accomplished by manipulating the advancing angle between printed layers, affects the survival of ovarian follicles. 30° and 60° scaffolds provide corners that surround follicles on multiple sides while 90° scaffolds have an open porosity that limits follicle–scaffold interaction. As the amount of scaffold interaction increases, follicle spreading is limited and survival increases. Follicle-seeded scaffolds become highly vascularized and ovarian function is fully restored when implanted in surgically sterilized mice. Moreover, pups are born through natural mating and thrive through maternal lactation. These findings present an in vivo functional ovarian implant designed with 3D printing, and indicate that scaffold pore architecture is a critical variable in additively manufactured scaffold design for functional tissue engineering.>>
Source : https://www.nature.com/articles/ncomms15261
En réponse à ROMÉRO pour son livre Homo Politicus et en continuité avec les livres Homo exoticus & Sexus Politicus/Diabolicus; à la suite de Pourquoi l'Amour est un plaisir de DIAMOND, en lisant The evolutionary biology of human female sexuality tout en passant par Platon en pensant à Foucault parce-que l'homosexualité est un phénomène social de grande échelle, autrement plus compliqué qu'une simple invention de médecins; En réponse aussi à Judith BUTLER préférant Martha NUSSBAUM
Inscription à :
Publier les commentaires (Atom)
Aucun commentaire:
Enregistrer un commentaire